As shown by Goat and Jin, even pulse guns work well as main weapons (with proper support from a teammate). EOs like GAEA and SELENA could be game changers too. O so many options.
Actually in the end, I didn't really care about the enemy's color since there's a big "Red/Blue Team 1/2" indicator on top of everybody.
but color scheme's do still play a role as a team with 2 widely different color schemes are more prone to FF that those with the more or less the same colors.